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17 Mayıs 2025, 03:43
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BGDS ve Sorumlu Oyun Common PAMPs include bacterial components like lipopolysaccharide (LPS) from Gram-negative bacteria (e.g., P. gingivalis), peptidoglycan, and flagellin [45]. sergisinin hangi alanda faaliyet gösterdiğine bakılmaksızın geniş bir tabana hitap eder. Firma katkıda bulunmayı yapabilir. They divide the protein genetic sequences from lysine or arginine residues: lysine-gingipain, arginine-gingipain A, and arginine-gingipain B [39]. P gingivalis the main pathogen that causes the majority of disease progression is a late colonizer of the complex process of bacterial aggregation, and it works in synergy with early colonizers like Streptococcus oralis, Streptococcus mitis, Streptococcus gordonii, Streptococcus, Streptococcus sanguis and intermediate colonizer such as Fusobacterium nucleatum which guarantees, directly or through Treponema denticola, the adhesion of P. gingivalis [40]. Phagocytes in Periodontitis: Neutrophils and MacrophagesPhagocytic cells, which include neutrophils, macrophages, and dendritic cells, play a critical role in defending the host against the microbial threat in periodontitis. Neutrophils are the first responders to microbial invasion in the gingiva and play a crucial role in controlling the bacterial load during the early stages of periodontitis [52]. Numerous studies have Nedir bgds also demonstrated the importance of neutrophils in preserving the periodontal tissue’s internal environment. Epithelial Cells and Barrier bgds nedir FunctionThe oral epithelium serves as the first physical barrier against microbial invasion. In the presence of periodontal pathogens, epithelial cells lining the gingiva and oral mucosa are essential in initiating the immune response [44]. Epithelial cells contain pattern recognition receptors (PRRs), which recognize pathogen-associated molecular patterns (PAMPs) unique to microorganisms.